Careers

Position Summary:

We are currently seeking a qualified, highly motivated, experienced individual for the position of Manager, Project Management reporting into the Associate Director, Project Management. The manager will develop project timelines and work cross-functionally to develop and then execute team goals, commitments and objectives. The position will collaborate closely with cross-functional team members, including clinical development, pre-clinical research, regulatory, and CMC functions.

Key Responsibilities:

• Develop project plans including timelines, budgets, and milestones.
• Coordinate and facilitate project team meetings effectively and practice good record keeping through minutes, action items, follow ups, etc.
• Plan, track and execute projects in alignment with clinical development strategy.
• Manage and identify risks and conflicts within the project and team.
• Develop and manage project budgets.
• Interact with external vendors as needed.

Preferred Education/Experience:

• Bachelor’s degree in scientific or healthcare related field with 5+ years of industry experience in biotech/pharmaceutical
• Master’s degree in scientific or healthcare related field with 3+ years of industry experience

Knowledge, Skills and Abilities:

• BS degree in scientific or healthcare required
• PMP certification a plus but not required
• 3+ years’ experience in clinical and drug development in biotech or pharma
• Efficient in Microsoft Project, Outlook, PowerPoint, and other computer programs
• In depth knowledge of the clinical development process and getting a program from preclinical to IND and Phase 1.
• Excellent verbal and written communication skills.
• Ability to drive projects and teams effectively to meet milestones and timelines required.
• Demonstrated ability to exercise independent judgment and strategic thinking with minimal supervision.
• Ability to multitask on multiple programs and projects and prioritize effectively.
• Capability to influence in a team setting.

We invite qualified candidates to submit their CV to: recruiting@appliedmt.com (note: ‘Please put job title in subject heading)

Position Summary:

AMT is seeking a South San Francisco based Head of Human Resources reporting to the Vice President, Finance and Business Operations.

As the first HR hire for the Company, you will have the opportunity (and responsibility) to build out our Human Resources infrastructure.

Key Responsibilities:

• Develop our people strategy to support the company’s business.
• Build strong and effective relationships with leadership team, managers and employees to become a trusted partner and coach throughout the organization.
• Identify gaps in culture, training and development, performance management and HR processes, and develop strategies and timelines to address these gaps based on business objectives.
• Lead, build and implement best practices in Human Resources to attract and retain talent and be competitive in the market.
• Proactively engage in succession planning discussions with leadership.
• Ensure HR processes are current and manage compliance with federal and state HR laws and regulations.
• Lead annual performance review process for the company.
• Establish and manage annual human resources budget.
• Participate on teams, committees and special products to help make a difference in the organization and establish a high performing and thriving company culture.

Preferred Education/Experience:

• Masters’ Degree, PHR-CA or SPHR Certification preferred
• 10+ years of progressive experience in human resources and experience in leading human resources for an entire company.
• Life sciences experience is highly preferred. Desire to work in a fast-paced highly collaborative small biotech environment.

Knowledge, Skills and Abilities:

• Proven leader in HR in areas such as employee relations, HR compliance/process, talent management, professional development, performance management, culture building and coach to leadership team 
• Excellent leadership, management, and organizational skills.
• Familiar with the use of PEO and how the service integrates with the Company.
• Able to juggle tactical and strategic priorities while maintaining clear focus on objectives.
• Results-driven professional that can produce outcomes with a focus on critical business demands while building trust, influencing and managing upwards and across the organization.
• An ability to quickly integrate into a culture and continue to cultivate an open door and open communication environment with a fun style and exceptionally high emotional intelligence.
• Must be confident and able to offer sound advice and lead the company’s HR direction.
• Proficient in MS Office with the ability to analyze data.
• Demonstrates clear and succinct written and verbal communication.
• Strong moral compass and the ability to provide ethical guidance to business partners.

We invite qualified candidates to submit their CV to: recruiting@appliedmt.com (note: ‘Please put job title in subject heading)

Position Summary:

We are seeking a skilled and experienced researcher to join a team focused on the expression and characterization of novel biologic drug candidates that modulate inflammation for the treatment of human diseases.

The successful candidate will be responsible for expressing, purifying, and characterizing recombinant proteins in support of discovery and preclinical development programs. Demonstrable experience with protein purification techniques and protein analytical/characterization methods is required. Experience with growth and transfection of mammalian cells up to liter scale for protein production will be a significant asset. Strong data analysis skills, the ability to prepare written reports, the ability to present results at research team meetings, and the ability to work productively and collaboratively within a tight-knit team are key assets for this position.

Key Responsibilities:

• Strong scientific grounding in protein chemistry and protein structure and function.
• Production of recombinant proteins up to liter scale from mammalian cell lines (e.g., CHO cells and HEK cells).
• Experience with bacterial expression and refolding of proteins highly desirable.
• Laboratory experience in protein purification (e.g. affinity chromatography, size exclusion chromatography, ion exchange chromatography).
• Laboratory experience in protein analytical techniques (e.g., SDS-PAGE, HPLC, Western Blot).
• Perform data analysis and summarize experimental results, with supervision as appropriate.
• Prepare and maintain cell culture reagents and media.
• Ensure sufficient laboratory supplies for daily laboratory operations.
• Organize, record and maintain experimental data.
• Ensure proper operation and perform routine maintenance of laboratory equipment.
• Assist other staff to complete laboratory tasks as necessary.
• Maintain a clean and safe work environment

Preferred Education/Experience:

• B.S. in Biochemical, Chemical, and Biology related discipline with 4-6 years of relevant experience or an MS with 2-4 years, or PhD with 0-2 years. Title and salary will be commensurate with the candidate’s qualifications.

Knowledge, Skills and Abilities:

• Must have excellent organization skills and ability to handle multiple tasks.
• Highly motivated, willingness to acquire new skills and ability to work with minimal supervision.
• Excellent verbal and written communication skills.
• Must be proficient in Microsoft Word, Excel, etc.

We invite qualified candidates to submit their CV to: recruiting@appliedmt.com (note: ‘Please put job title in subject heading)

Position Summary:

We are currently seeking a Research Associate to join our team. This individual will be motivated and thrives as part of cross-functional team within Applied Molecular Transport. This an exciting opportunity for an individual motivated to see his work directly impact the development of our lead molecule. The successful candidate will be a bench research associate and key member of the biological sciences. The candidate will help to advance programs from discovery to IND/CTA filing.

Key Responsibilities:

• Develop and perform in vivo, ex vivo, and in vitro studies.
• Assist in developing and performing PK/PD assays for multiple animal models.
• Generate reports and presentations for cross-functional team meetings.
• Actively participate in team meetings to discuss and review data.

Preferred Education/Experience:

• A Bachelor’s/Master’s degree or equivalent experience in pharmacology, physiology, biology, or relevant degree with at least 2 years of hands-on work experience in a biotech or pharma setting.
• Proficiency in designing and executing a variety of in vivo, ex vivo and in vitro studies.

Knowledge, Skills and Abilities:

• Passion to maintain current scientific knowledge focused on pharmacology, toxicology and molecular pharmacology.
• Comfortable at working independently and managing multiple projects in a fast-paced environment.
• Familiarity with animal model development across inflammatory and metabolic diseases.
• Proficiency in designing and executing in vivo PK/PD studies.
• Proficiency with various in vivo skills including dosing (IV, SC, IP, PO), bleeding and harvesting/processing of tissue is a must.
• Experience with ELISA, Western blotting, RT-qPCR, flow cytometry, microscopy and histology is required; experience with Meso Scale Discovery system is a plus.
• Working knowledge of PK/PD principles and software (e.g., WinNonlin, NONMEM, SimBiology, etc)
• Expertise in data analysis software: MS PowerPoint, MS Excel, MS Word and GraphPad Prism.
• The ability to be innovative and creatively solve problems.
• Outstanding written, verbal, and presentation skills are a must.

We invite qualified candidates to submit their CV to: recruiting@appliedmt.com (note: ‘Please put job title in subject heading)

Position Summary:

We are currently seeking a Senior Scientist to join our team. This individual will be motivated and thrives as part of cross-functional team within Applied Molecular Transport. This an exciting opportunity for an individual motivated to see his work directly impact the development of our lead molecule. The successful candidate will be a Senior Scientist and key member of the biological sciences. The candidate will help to advance programs from discovery to IND/CTA filing.

Key Responsibilities:

• Develop and lead the analysis of preclinical (PK, ADA, biomarker) samples in support of various stage of preclinical and clinical studies.  
• Perform primary (QC) data review for the assays and results
• Trouble shoot assay performance.
• Generate reports and presentations for cross-functional team meetings.
• Actively participate in team meetings to discuss and review data.

Preferred Education/Experience:

• A Bachelor’s/Master’s degree or equivalent experience in biology, or relevant degree with at least 10 years of hands-on work experience in Bio Analytical in a biotech or pharma setting.
• Experience on IND and EMA filing.
• Proficiency in designing and executing a variety of Bio Analytical Methods (PK/PD and ADA assays, analytical immunoassays including antibody binding assays, ELISA, MSD, Luminex, biosensor, flow cytometry, SDS-PAGE or HPLC).

Knowledge, Skills and Abilities:

• Passion to maintain current scientific knowledge focused on Bio Analytical Methods.
• Comfortable at working independently and managing multiple projects in a fast-paced environment.
• Experience and knowledge in polyclonal and monoclonal antibody generation using hybridoma, phage display, and/or B-cell approaches.
• A strong background in immunology, antibody characterization and immunoassay development.
• Manage sample logistics and Partner with CROs to manage and monitor outsourced PK/ADA assays.
• Extensive track record of successfully developing bioanalytical methods for biopharmaceuticals.
• The ability to be innovative and creatively solve problems.

We invite qualified candidates to submit their CV to: recruiting@appliedmt.com (note: ‘Please put job title in subject heading)

Position Summary:

Applied Molecular Transport, Inc. is looking to hire a research associate in analytical method development and quality control (AD & QC) for its therapeutic programs. The successful candidate will have extensive understanding of protein chemistry, protein characterization, and analytical techniques. The position will involve regular communication and collaboration with an interdisciplinary team within AMT and with outside contractors/consultants.

Key Responsibilities:

• Perform analytical method development for LC based assays such as SEC, IEX and reversed-phase HPLC, and other protein-based analysis (i.e. SDS-PAGE, western blot, A280)
• Provide testing support for the in-house manufacture of drug substance and drug product
• Execute stability studies to evaluate and characterize protein degradation during storage
• Process data and present findings at regular team meetings
• Write technical reports
• Document operating procedures for technology transfer and work with CROs/CMOs to implement methods in a GMP environment

Preferred Education/Experience:

• BS, MS, PhD or equivalent degree in chemistry, biochemistry, biological sciences, pharmaceutical sciences or a related discipline
• 1-5 years of experience in the biotech/pharmaceutical industry

Knowledge, Skills and Abilities:

• Practical experience with protein chemistry, degradation and stabilization mechanisms
• Experience with HPLC, electrophoresis, UV-vis spectroscopy and other analytical methods
• Interpersonal skills and ability to contribute to the success of a team
• Strong written and verbal communication skills
• Time management skills and ability to meet deadlines
• Additional analytical techniques: cIEF, mass spec, ELISA, bioassay, peptide mapping
• Experience with solid dosage form analysis (i.e. dissolution, particle sizing)
• Experience in GLP or GMP environment
• Management of external CROs/CMOs a plus

We invite qualified candidates to submit their CV to: recruiting@appliedmt.com (note: ‘Please put job title in subject heading)