Careers

Position Summary:
Provides administrative support to the senior executives.

Key Responsibilities:

• Organizes and maintains executive calendar meetings. Exercises considerable judgment and discretion in handling requests for appointments and ensures all parties are informed of and kept abreast of schedules and schedule changes and conflicts.
• Support coordination, preparation and planning activities for AMT BOD meetings. This includes scheduling and confirming BOD attendance, assisting in the preparation of PowerPoint presentations and ensuring that the meeting room, equipment and refreshments are prepared in advance.
• Effectively handle as much as possible on behalf of the executive officers, but exercise good discretion and judgment with regard to involving them as appropriate.
• Ability to develop, implement, understand general company operations, workflows, and procedures as appropriate.
• Demonstrates a high level of professionalism in dealing with confidential and sensitive issues.
• Coordinates executive travel arrangements.
• Composes, types, and distributes professional correspondence, memoranda and E-mails, using individual initiative and as assigned. Creates PowerPoint presentations and some spreadsheets as required.
• Prepares work agreements and proposals and maintains appropriate records and files.
• Assist with project tracking and project status updates.

Preferred Education/Experience:

• Bachelor’s degree is preferred.
• 3-6 years of experience as an Executive Administrative support at the senior executive level.
• Experience in a smaller medical device or biotech company preferred.
• Experience in a high growth, dynamic startup environment preferred.

Knowledge, Skills and Abilities:

• Strong organizational, attention to detail, problem-solving, and analytical skills; able to multi-task, manage priorities and workflow.
• Ability to work independently and as a member of various teams and committees.
• Knowledge of office administration responsibilities, systems and procedures.
• Dependable, flexible, ethical and hardworking professional – must be a team player.
• Must be proficient with Microsoft Word, PowerPoint and Outlook.
• Excellent written skills with attention to detail, time management and organizational skills.
• Ability to communicate effectively with outside contacts and all levels of company personnel.

AMT is an equal opportunity employer. In accordance with applicable law, AMT does not discriminate in hiring or otherwise in employment based on race, color, religion, sex, national origin, age, marital or veteran status, disability, sexual orientation, or any other legally protected status. EOE/AA/Vets

Please include a cover letter in your application

Company

Applied Molecular Transport (AMT) is a biopharmaceutical company with a transformative platform technology that enables the development of next generation biological therapeutics, with a particular focus on oral, site-specific targeting to the GI tract as well as to systemic circulation. The company’s core pipeline therapeutic area strategy is focused on Immunology & Inflammation and Metabolic Diseases.

This role is a unique opportunity in an energetic company that is based on exciting foundational scientific principles with the prospect of transforming the biological therapeutics landscape and thus, beneficially impacting the lives of millions of patients. The company’s management and founders collectively have decades of R&D, business, and leadership experience at organizations such as Amgen, Chiron, Onyx, ALZA, Five Pri­­me, Second Genome, NGM and Genentech.

Job Overview

The successful candidate will join the downstream processes (DSP) purification group. In this role, protocols for protein purification and in-process analysis and characterization of intermediate purified proteins will be developed for heterologous fusion proteins from bacterial source. The development of purification processes will include protein solubilization, refolding, UFDF and protein separation by column chromatography using AKTA systems. A variety of protein separation techniques by column chromatography will be used with purification principals ranging from Ion exchange chromatography (IEC), hydrophobic interactions chromatography (HIC), mixed-mode chromatography, size-based purification such as size exclusion/gel filtration, and affinity purification strategies.

Key Responsibilities:

• Develop protein purification protocols using AKTA FPLC systems working with a variety of resins in scales ranging from 5 mL to 5.0 L columns, and a variety of buffers
• Develop Ultrafiltration/Diafiltration (UFDF) application suitable for scale-up and scale-down purifications
• Optimize depth filtration processes to enable feed stock clarification
• Perform in-process analytics utilizing techniques such SDS-PAGE, SEC-HPLC, Reverse phase chromatography, protein solutions spectroscopic and colorimetric measurments, as well as quantitative SEC-HPLC to determine protein concentration of various samples
• Provide technical and scientific support to AMT manufacturing facility by executing a wide range of tests, from adjusting buffer recipes and testing buffer reagents to full-scale DSP purification procecesses in a scale-down format

Required Skills

• Thorough understanding of protein purification concepts including the chemistry of a variety of preperative resins for protein chromatography
• Understanding the requirements of process scale-up
• Proficient in downstream purification using Unicorn system on AKTA systems
• Experience with preparative column packing ranging from 5 – 300 mL
• Familiarity with protein analytical techniques to perform assays such as SEC-HPLC,  SDS-PAGE, Reverse Phase chromatography, spectroscopy, turbidity, and endotoxin levels measurments
• Experience in TFF (ultra-filtration, diafiltration) depth filtration and chromatography
• Experience in protein concentration measurement methods such spectroscopy (280 nM), colorimetric methods such as Bradford assay, and chromatography methods such as quantitative SEC-HPLC
• Experience in protein refolding from E. coli inclusion body is desirable
• Ability to work well with multidisciplinary teams
• Computer programs: Unicorn 7.0 and above, OpenLab, Chemstation, Chromeleon, MS PowerPoint, MS Excel, SoftMax Pro, MS Word, and JMP.
• Demonstrate technical proficiency in designing, and developing purification processes for proteins expressed in microbial hosts is a plus

Required Experience/Qualification

• individual holding a BA/BS or Master degree with 2-4 years of hands-on experience in protein purification in a biotech or biopharmaceutical companies
• Hands on experience with AKTA FPLCs
• Experienced in summarizing projects in the form of written reports that are both concise and include the relevant and important details
• Strong desire to learn multiple new techniques and willingness to work as part of team
• Preenting the work in meetings

We invite qualified candidates to submit their CV to: recruiting@appliedmt.com (note: ‘Please put job title in subject heading)

AMT is an equal opportunity employer. In accordance with applicable law, AMT does not discriminate in hiring or otherwise in employment based on race, color, religion, sex, national origin, age, marital or veteran status, disability, sexual orientation, or any other legally protected status. EOE/AA/Vets

Position Summary:

The Clinical Trial Specialist (CTS) will support the Clinical Trial Managers to ensure the success of current and future clinical trials at AMT. The CTS will work with the CTM to assist with the planning and implementation of multiple studies within a clinical development program. The position will also work closely with other cross-functional representatives including Regulatory, Clinical Development, Project Management, and QA to ensure successful completion of all clinical activities/project deliverables within the required time frame. The position will also support oversight of the CRO and other third-party vendors on the assigned study. This individual will report to a Clinical Trial Manager.

Key Responsibilities:

• Assist CTMs with activities related to study start-up; investigator site feasibility and selection; essential document review related to investigator site initiation and investigational product release and patient enrollment.
• Assist with tracking, reviewing, distribution, and storage of key internal and external documents such as investigator brochures, protocols, interim safety reports, and site/subject material, through the course of the study.
• Maintains and disseminates basic study tracking information including, but not limited to: Visit Reports, Regulatory Documents, Site Contact Lists, Team Contact Lists, Vendor metrics, and Enrollment metrics.
• Assists CTMs with the oversight of CRO(s) and other study-related, third-party vendors to ensure study requirements are met and study documents are delivered to the Sponsor in a timely manner.
• Track study wide clinical supply inventory, vendor supplies at sites and management of study samples.
• Ensures electronic trial master files (eTMF) are compliant with relevant regulatory requirements by performing periodic and ad hoc reviews/audits of TMF. This includes the reconciliation of the TMF at study close-out and responding to TMF related inquiries.
• Maintains and ensures all documentation is in a state of audit-readiness.
• Utilize project management tools (e.g. Outlook, Word, PowerPoint, Timelines, Excel) in order to plan and execute effective meetings with appropriate materials and balance scope and schedule for each trial.
• Creates meeting agenda/minute templates and provides drafts of meeting minutes.
• Support clinical team efforts to track and contribute to regulatory submissions in the US and globally by coordinating and tracking approvals of clinical documents.
• Ensures Good Clinical Practices are followed, ensures protocol deviations are properly recorded, SOPs are maintained and routinely updated, and CRO/site audits are tracked.
• Coordinate collection, tracking, and maintenance of updated site regulatory documentation (i.e. FDFs, 1572s, CVs, IRB approvals, etc.).
• Develop working knowledge of company standard operating procedures (SOPs) and familiarity with FDA and global regulations related to clinical studies.
• Participates in organizing investigator meetings including venue selection, invitations, agenda, and materials distribution.
• Communicates effectively with members of the AMT and vendor project teams.
• Other tasks or responsibilities as assigned.

Preferred Education/Experience:

• A Bachelor’s or Associate’s degree is required. A BA or BS in biological sciences, nursing, or related field is preferred. Prior CTA experience and exposure to clinical trial operations is preferred.

Knowledge, Skills and Abilities:

• Knowledge and/or experience of operational aspects of all stages of clinical studies, knowledge of Good Clinical Practice (GCP) and International Conference on Harmonisation (ICH) guidelines.
• Familiar with using eTMF, EDC, IRT, CTMS, SharePoint and other vendors systems/portals.
• Thrives in a dynamic start‐up environment with busy, high performing colleagues; flexibility to wear multiple hats as needed.
• Ability to learn quickly and effectively using newly acquired skills, ability to use time efficiently, multi-task, prioritize, track projects, and follow-through on-time with assigned tasks with exceptional attention to detail.
• Excellent organizational and communication skills: Is able to listen and follow instructions; asks questions or clarifications as needed; is transparent and able to communicate clearly and effectively.
• Demonstrates accuracy, thoroughness, and thoughtfulness; is able to assess strengths and development areas; Provides quality deliverables and strives to continuously build knowledge and skills.
• Strong work ethic; A motivated, positive minded individual who is proactive, flexible and solution oriented to address changing program needs in real time.
• Team player who is collaborative, accountable, self-aware; works well in a team environment but can also work independently without significant oversight.
• Contributes to building a positive team spirit and company culture; Supports everyone’s efforts to succeed; Shares expertise with others.
• Ability to build strong relationships with co-workers of various backgrounds and expertise.

We invite qualified candidates to submit their CV to: recruiting@appliedmt.com (note: ‘Please put job title in subject heading)

AMT is an equal opportunity employer. In accordance with applicable law, AMT does not discriminate in hiring or otherwise in employment based on race, color, religion, sex, national origin, age, marital or veteran status, disability, sexual orientation, or any other legally protected status. EOE/AA/Vets

AMT’s novel, proprietary mucosal immunology-based platform allows for the development of biopharmaceuticals that by their oral delivery will enable, or at the very least enhance, previously unattainable or unappreciated biological outcomes for agents delivered by the oral-GI route. The company’s current core therapeutic areas of focus are Immunology & Inflammation and Metabolic Diseases.

Position Summary:

Manage the accounting function for the organization and is accountable for staff involved in the daily activities of the accounting department.

Key Responsibilities:

• Responsible the monthly/quarterly close process for general ledger accounts and related activities for the production of financial statements and reports.
• Manage clinical trial accounting and equity accounting.
• Responsible for Accounts Payable including primary contact with collaborations regarding billing matters.
• Supervise the Accounting Analyst and Payroll Specialist including training, goal setting, and performance management. Provide back-up duties for payroll and accounts payable processing as required. 
• Perform account reconciliations and analyses, prepare journal entries and review accounting classifications, in accordance with generally accepted accounting principles.
• Analyze and prepare financial statements, including balance sheets, statements of financial position, and cash flow statement.
• Assist with development and maintenance of internal control structure. Ensure compliance with established controls.
• Assist with identification, documentation, and adherence to the Company’s financial policies.
• Prepare documentation in support of external quarterly reviews and annual audits including interfacing with auditors and responding to questions. Review audit reports and make process changes as appropriate. 
• Coordinate and assist outside tax consultants with preparation of tax provisions and filings.
• Identify process improvements. Develop and implement supporting policies and/or procedures.
• Other ad hoc projects as needed.

Required Education/Experience:

• Bachelor’s Degree in Accounting or Finance.
• 7-10 years of accounting experience
• Biotech and previous management experience preferred.
• CPA preferred.

Knowledge, Skills and Abilities:

• Strong knowledge of Generally Accepted Accounting Principles.
• Detail oriented, analytical, and accurate.
• Exceptional communication skills that provide the ability to interact with all levels of the organization with a high customer service orientation.
• Proficient computer skills specifically PowerPoint and excel
• Strong work ethic and demonstrated ability to independently prioritize workload based on organizational needs/demands. Operates with a sense of urgency, as appropriate.
• Self-starter.
• Creative problem solver who anticipates risks and opportunities and maintains a vision for continuous improvement.

We invite qualified candidates to submit their CV to: recruiting@appliedmt.com (note: ‘Please put job title in subject heading)

AMT is an equal opportunity employer. In accordance with applicable law, AMT does not discriminate in hiring or otherwise in employment based on race, color, religion, sex, national origin, age, marital or veteran status, disability, sexual orientation, or any other legally protected status. EOE/AA/Vets

Position Summary:

Applied Molecular Transport, Inc. has an exciting new opportunity for a Research Associate in the Pharmaceutical Science department. This position will develop novel drug dosage forms for AMT pipeline molecules. The successful candidate will have good understanding of protein chemistry, protein characterization and purification, and strong work responsibility and reliability in a fast-paced drug research environment.

Key Responsibilities:

• This is a laboratory-based position.
• Perform experiments to support AMT drug discovery and development programs.
• Conduct pharmaceutical studies such as drug formulation, dissolution test and bioconjugation.
• Characterize drug samples using spectroscopic and chromatography analytical methods such as SEC, RP-HPLC, UV and light scattering.
• Analyze, interpret, and accurately record experimental data.
• Participate in group meetings, compile and present data for team review.
• Document and maintain material inventories and sample logs.

Required Experience/Education:

• BS/MS in chemistry, biochemistry, or related discipline.
• 1-3 years of lab experience in biotech/pharmaceutical industrial setting.

Knowledge, Skills and Abilities:

• Experience in wet lab experiments such as chemical reagent handling, chemical and biological sample preparation.
• Experience in analytical techniques and instrumentation such as HPLC/UPLC, UV, AKTA, gel electrophoresis. Knowledgeable in protein chemistry, protein purification and bioconjugation.
• Attention to detail and can-do attitude.  Work independently as well as in team setting.
• Strong communication skills and computer skills such as Microsoft Word, Excel, PowerPoint etc.

We invite qualified candidates to submit their CV to: recruiting@appliedmt.com (note: ‘Please put job title in subject heading)

AMT is an equal opportunity employer. In accordance with applicable law, AMT does not discriminate in hiring or otherwise in employment based on race, color, religion, sex, national origin, age, marital or veteran status, disability, sexual orientation, or any other legally protected status. EOE/AA/Vets

Position Summary:

The Clinical Trial Manager/Senior Clinical Trials Manager will be responsible for the operational management and oversight of clinical trials within a clinical development program. The position will work closely with the Medical Monitor and other cross-functional representatives including Clinical Data Management, Biostatistics, Regulatory/QA, Pharmacology and Biology to ensure successful completion of all clinical activities/project deliverables within the required time frame and budget. The position will also provide oversight of the CRO and other third-party vendors on the assigned study. This individual will report into the Head of Clinical Operations.

Key Responsibilities:

• Responsible for the planning, implementation and conduct of large, global, complex clinical trials in Phase I-IV; or multiple smaller early-phase studies. 
• Responsible for oversight and project management of individual studies as well as relevant program related activities with minimal supervision. 
• Provides leadership within the department and makes recommendations with regards to the operational aspects of executing clinical development deliverables.   
• Actively provides operational direction and/or general supervision to direct reports
• Assist with training and mentoring of internal clinical operations staff. 
• Establish study milestones and ensure accurate tracking and reporting of study metrics and timelines. 
• Manage CROs, vendors and consultants that are involved with the clinical trial and program. 
• Track and report on progress of study including site activation, patient enrollment, monitoring visits
• Perform clinical data review of data listings and summary tables, including query generation  
• Identify, select, and monitor performance of investigational sites for clinical studies; prepare accurate and timely visit reports from all site interaction visits
• Develop and maintain good working relationships with investigators and study staff
• Ensure studies are carried out according to the study protocol, SOPs, and ICH/GCP regulations and study-specific manuals and procedures
• Review key study quality metrics (e.g., eligibility, primary endpoint data, etc.) and determine appropriate action in conjunction with study team (autonomy may vary with experience)
• Investigate queries, monitor discrepancies
• Manage investigational product (IP) accountability and reconciliation process
• Responsible for review or approval of IP release packages
• Negotiate and manage the budget and payments for investigative sites
• Develop CRA and third-party vendor training on protocols and practices 
• Participate in program strategy meetings, ad hoc clinical operations’ initiatives and programs as assigned. 
• Write or contribute to the preparation of clinical protocols, amendments, informed consent forms, study guides, case report forms, and any other clinical research related documents
• Perform initial review of CRO and other third-party study vendor invoices to ensure that work is performed in accordance with scope of work
• Responsible for the planning, implementation and conduct of large, global, complex clinical trials in Phase I-IV; or multiple smaller early-phase studies. 
• Responsible for oversight and project management of individual studies as well as relevant program related activities with minimal supervision. 
• Provides leadership within the department and makes recommendations with regards to the operational aspects of executing clinical development deliverables.   
• Actively provides operational direction and/or general supervision to direct reports
• Assist with training and mentoring of internal clinical operations staff. 
• Establish study milestones and ensure accurate tracking and reporting of study metrics and timelines. 
• Manage CROs, vendors and consultants that are involved with the clinical trial and program. 
• Track and report on progress of study including site activation, patient enrollment, monitoring visits
• Perform clinical data review of data listings and summary tables, including query generation  
• Identify, select, and monitor performance of investigational sites for clinical studies; prepare accurate and timely visit reports from all site interaction visits
• Develop and maintain good working relationships with investigators and study staff
• Ensure studies are carried out according to the study protocol, SOPs, and ICH/GCP regulations and study-specific manuals and procedures
• Review key study quality metrics (e.g., eligibility, primary endpoint data, etc.) and determine appropriate action in conjunction with study team (autonomy may vary with experience)
• Investigate queries, monitor discrepancies
• Manage investigational product (IP) accountability and reconciliation process
• Responsible for review or approval of IP release packages
• Negotiate and manage the budget and payments for investigative sites
• Develop CRA and third-party vendor training on protocols and practices 
• Participate in program strategy meetings, ad hoc clinical operations’ initiatives and programs as assigned. 
• Write or contribute to the preparation of clinical protocols, amendments, informed consent forms, study guides, case report forms, and any other clinical research related documents
• Perform initial review of CRO and other third-party study vendor invoices to ensure that work is performed in accordance with scope of work

Preferred Education/Experience:

• Bachelor’s degree or higher in a scientific or healthcare discipline preferred with minimum of 5-7 years of progressive experience in clinical research and clinical operations preferably within the biotech, pharmaceutical sector, or CRO environment. Prior experience managing people is desired.

Knowledge, Skills and Abilities:

• Extensive experience managing clinical programs, CROs, budgets, and timelines required
• Proven experience in the oversight of the operational aspects of all stages of clinical studies
• Ability to organize and manage multiple priorities required
• Ability to thrive in a fast-paced, entrepreneurial environment with busy, high performing colleagues
• Ability to function at a high level in a team setting whether leading the group or acting as an individual contributor
• Proactive and positive management approach
• Maximum flexibility to adapt to changing program needs in real time
• Strong leadership skills and self-awareness
• Ability to build strong relationships with co-workers of various backgrounds and expertise

We invite qualified candidates to submit their CV to: recruiting@appliedmt.com (note: ‘Please put job title in subject heading)

AMT is an equal opportunity employer. In accordance with applicable law, AMT does not discriminate in hiring or otherwise in employment based on race, color, religion, sex, national origin, age, marital or veteran status, disability, sexual orientation, or any other legally protected status. EOE/AA/Vets

Position summary:

We are seeking a talented and dynamic scientist to lead efforts in the discovery and development of novel, oral biological therapeutics to treat severe autoimmune, metabolic and inflammatory diseases. The successful candidate will responsible for the design and implementation of nonclinical programs aimed at identifying and characterizing novel therapeutics and will work in close collaboration with teams throughout the organization, including biology, protein sciences, CMC, regulatory affairs, and clinical development.

Key responsibilities:

• Lead cross-functional nonclinical teams to execute development strategies to generate, analyze, and summarize data from studies for inflammatory disease programs.
• As a leader in the organization, you will successfully maintain alignment and excellent communications with key stakeholders internally, and ably represent AMT to external collaborators and in public presentations.
• Author nonclinical pharmacology reports and nonclinical pharmacology sections of regulatory documents.
• Additional activities include managing and identifying key external collaborations that will enhance and/or expedite decisions on projects and/or yield new target opportunities.

Preferred Education/Experience:

• Applicants must have a PhD or equivalent degree and at least 8 years of relevant post graduate experience, preferably in industry.
• Demonstrated experience in target discovery, translational research, and drug development is strongly preferred. Direct experience in the investigation of pathways or interventional targets related to mucosal immunology and inflammatory bowel disease is optimal.

Knowledge, Skills and Abilities

• Excellent communication skills (both written and verbal) and interpersonal skills are required. Must think critically and creatively and be able to work independently, determine appropriate resources for resolution of problems and have strong organizational and planning skills.
• The successful candidate must have demonstrated an ability to manage several projects at any given time, to work successfully in a cross-functional and highly collaborative team environment, and to communicate clearly and effectively both verbally and in writing to a variety of audiences.
• Previous project leadership in drug discovery preferred
• Experience authoring of technical reports, drug discovery documents, and regulatory submissions desired
• Demonstrated scientific leadership, mentoring and organizational skills with respect to both managing direct reports as well as external collaborations and/or CROs.

We invite qualified candidates to submit their CV to: recruiting@appliedmt.com (note: ‘Please put job title in subject heading)

AMT is an equal opportunity employer. In accordance with applicable law, AMT does not discriminate in hiring or otherwise in employment based on race, color, religion, sex, national origin, age, marital or veteran status, disability, sexual orientation, or any other legally protected status. EOE/AA/Vets

Position summary:

We are seeking a talented and dynamic scientist to lead biomarker efforts for novel, oral biological therapeutics to treat severe autoimmune, metabolic and inflammatory diseases. The successful candidate will responsible for the design and implementation of biomarker strategies aimed for novel therapeutics and will work in close collaboration with teams throughout the organization, including biology, protein sciences, CMC, regulatory affairs, and clinical development.

Key responsibilities:

• Lead the development and execution of translational and biomarker discovery and development strategies for non-clinical and clinical studies within inflammation.
• As a leader in the organization, you will successfully maintain alignment and excellent communications with key stakeholders internally, and ably represent AMT to external collaborators and in public presentations.
• Author biomarker study reports and biomarker sections of regulatory documents.
• Identify and manage key external collaborations to enhance project decisions and/or yield new target opportunities.

Preferred Education/Experience:

• Applicants must have a PhD or equivalent degree and at least 8 years of relevant post graduate experience, preferably in industry, with direct experience in research drug discovery and target validation in inflammatory diseases.
• Demonstrated experience in translational research and drug development is strongly preferred. Direct experience in the investigation of pathways or interventional targets related to mucosal immunology and inflammatory bowel disease is optimal.

Knowledge, Skills and Abilities:

• Excellent communication skills (both written and verbal) and interpersonal skills are required. Must think critically and creatively and be able to work independently, determine appropriate resources for resolution of problems and have strong organizational and planning skills.
• The successful candidate must have demonstrated an ability to manage several projects at any given time, to work successfully in a cross-functional and highly collaborative team environment, and to communicate clearly and effectively both verbally and in writing to a variety of audiences.
• Previous project leadership in translational sciences preferred
• Experience authoring of technical reports, drug discovery documents, and regulatory submissions desired
• Demonstrated scientific leadership, mentoring and organizational skills with respect to both managing direct reports as well as external collaborations and/or CROs.

We invite qualified candidates to submit their CV to: recruiting@appliedmt.com (note: ‘Please put job title in subject heading)

AMT is an equal opportunity employer. In accordance with applicable law, AMT does not discriminate in hiring or otherwise in employment based on race, color, religion, sex, national origin, age, marital or veteran status, disability, sexual orientation, or any other legally protected status. EOE/AA/Vets

Position Summary:

We are currently seeking a qualified, highly motivated, experienced individual for the position of Manager, Project Management reporting into the Associate Director, Project Management. The manager will develop project timelines and work cross-functionally to develop and then execute team goals, commitments and objectives. The position will collaborate closely with cross-functional team members, including clinical development, pre-clinical research, regulatory, and CMC functions.

Key Responsibilities:

• Develop project plans including timelines, budgets, and milestones.
• Coordinate and facilitate project team meetings effectively and practice good record keeping through minutes, action items, follow ups, etc.
• Plan, track and execute projects in alignment with clinical development strategy.
• Manage and identify risks and conflicts within the project and team.
• Develop and manage project budgets.
• Interact with external vendors as needed.

Preferred Education/Experience:

• Bachelor’s degree in scientific or healthcare related field with 5+ years of industry experience in biotech/pharmaceutical
• Master’s degree in scientific or healthcare related field with 3+ years of industry experience

Knowledge, Skills and Abilities:

• BS degree in scientific or healthcare required
• PMP certification a plus but not required
• 3+ years’ experience in clinical and drug development in biotech or pharma
• Efficient in Microsoft Project, Outlook, PowerPoint, and other computer programs
• In depth knowledge of the clinical development process and getting a program from preclinical to IND and Phase 1.
• Excellent verbal and written communication skills.
• Ability to drive projects and teams effectively to meet milestones and timelines required.
• Demonstrated ability to exercise independent judgment and strategic thinking with minimal supervision.
• Ability to multitask on multiple programs and projects and prioritize effectively.
• Capability to influence in a team setting.

We invite qualified candidates to submit their CV to: recruiting@appliedmt.com (note: ‘Please put job title in subject heading)

AMT is an equal opportunity employer. In accordance with applicable law, AMT does not discriminate in hiring or otherwise in employment based on race, color, religion, sex, national origin, age, marital or veteran status, disability, sexual orientation, or any other legally protected status. EOE/AA/Vets

Position Summary:

AMT is seeking a South San Francisco based Head of Human Resources reporting to the Vice President, Finance and Business Operations.

As the first HR hire for the Company, you will have the opportunity (and responsibility) to build out our Human Resources infrastructure.

Key Responsibilities:

• Develop our people strategy to support the company’s business.
• Build strong and effective relationships with leadership team, managers and employees to become a trusted partner and coach throughout the organization.
• Identify gaps in culture, training and development, performance management and HR processes, and develop strategies and timelines to address these gaps based on business objectives.
• Lead, build and implement best practices in Human Resources to attract and retain talent and be competitive in the market.
• Proactively engage in succession planning discussions with leadership.
• Ensure HR processes are current and manage compliance with federal and state HR laws and regulations.
• Lead annual performance review process for the company.
• Establish and manage annual human resources budget.
• Participate on teams, committees and special products to help make a difference in the organization and establish a high performing and thriving company culture.

Preferred Education/Experience:

• Masters’ Degree, PHR-CA or SPHR Certification preferred
• 10+ years of progressive experience in human resources and experience in leading human resources for an entire company.
• Life sciences experience is highly preferred. Desire to work in a fast-paced highly collaborative small biotech environment.

Knowledge, Skills and Abilities:

• Proven leader in HR in areas such as employee relations, HR compliance/process, talent management, professional development, performance management, culture building and coach to leadership team 
• Excellent leadership, management, and organizational skills.
• Familiar with the use of PEO and how the service integrates with the Company.
• Able to juggle tactical and strategic priorities while maintaining clear focus on objectives.
• Results-driven professional that can produce outcomes with a focus on critical business demands while building trust, influencing and managing upwards and across the organization.
• An ability to quickly integrate into a culture and continue to cultivate an open door and open communication environment with a fun style and exceptionally high emotional intelligence.
• Must be confident and able to offer sound advice and lead the company’s HR direction.
• Proficient in MS Office with the ability to analyze data.
• Demonstrates clear and succinct written and verbal communication.
• Strong moral compass and the ability to provide ethical guidance to business partners.

We invite qualified candidates to submit their CV to: recruiting@appliedmt.com (note: ‘Please put job title in subject heading)

AMT is an equal opportunity employer. In accordance with applicable law, AMT does not discriminate in hiring or otherwise in employment based on race, color, religion, sex, national origin, age, marital or veteran status, disability, sexual orientation, or any other legally protected status. EOE/AA/Vets

Position Summary:

We are seeking a skilled and experienced researcher to join a team focused on the expression and characterization of novel biologic drug candidates that modulate inflammation for the treatment of human diseases.

The successful candidate will be responsible for expressing, purifying, and characterizing recombinant proteins in support of discovery and preclinical development programs. Demonstrable experience with protein purification techniques and protein analytical/characterization methods is required. Experience with growth and transfection of mammalian cells up to liter scale for protein production will be a significant asset. Strong data analysis skills, the ability to prepare written reports, the ability to present results at research team meetings, and the ability to work productively and collaboratively within a tight-knit team are key assets for this position.

Key Responsibilities:

• Strong scientific grounding in protein chemistry and protein structure and function.
• Production of recombinant proteins up to liter scale from mammalian cell lines (e.g., CHO cells and HEK cells).
• Experience with bacterial expression and refolding of proteins highly desirable.
• Laboratory experience in protein purification (e.g. affinity chromatography, size exclusion chromatography, ion exchange chromatography).
• Laboratory experience in protein analytical techniques (e.g., SDS-PAGE, HPLC, Western Blot).
• Perform data analysis and summarize experimental results, with supervision as appropriate.
• Prepare and maintain cell culture reagents and media.
• Ensure sufficient laboratory supplies for daily laboratory operations.
• Organize, record and maintain experimental data.
• Ensure proper operation and perform routine maintenance of laboratory equipment.
• Assist other staff to complete laboratory tasks as necessary.
• Maintain a clean and safe work environment

Preferred Education/Experience:

• B.S. in Biochemical, Chemical, and Biology related discipline with 4-6 years of relevant experience or an MS with 2-4 years, or PhD with 0-2 years. Title and salary will be commensurate with the candidate’s qualifications.

Knowledge, Skills and Abilities:

• Must have excellent organization skills and ability to handle multiple tasks.
• Highly motivated, willingness to acquire new skills and ability to work with minimal supervision.
• Excellent verbal and written communication skills.
• Must be proficient in Microsoft Word, Excel, etc.

We invite qualified candidates to submit their CV to: recruiting@appliedmt.com (note: ‘Please put job title in subject heading)

AMT is an equal opportunity employer. In accordance with applicable law, AMT does not discriminate in hiring or otherwise in employment based on race, color, religion, sex, national origin, age, marital or veteran status, disability, sexual orientation, or any other legally protected status. EOE/AA/Vets

Position Summary:

Applied Molecular Transport, Inc. is looking to hire a research associate in analytical method development and quality control (AD & QC) for its therapeutic programs. The successful candidate will have extensive understanding of protein chemistry, protein characterization, and analytical techniques. The position will involve regular communication and collaboration with an interdisciplinary team within AMT and with outside contractors/consultants.

Key Responsibilities:

• Perform analytical method development for LC based assays such as SEC, IEX and reversed-phase HPLC, and other protein-based analysis (i.e. SDS-PAGE, western blot, A280)
• Provide testing support for the in-house manufacture of drug substance and drug product
• Execute stability studies to evaluate and characterize protein degradation during storage
• Process data and present findings at regular team meetings
• Write technical reports
• Document operating procedures for technology transfer and work with CROs/CMOs to implement methods in a GMP environment

Preferred Education/Experience:

• BS, MS, PhD or equivalent degree in chemistry, biochemistry, biological sciences, pharmaceutical sciences or a related discipline
• 1-5 years of experience in the biotech/pharmaceutical industry

Knowledge, Skills and Abilities:

• Practical experience with protein chemistry, degradation and stabilization mechanisms
• Experience with HPLC, electrophoresis, UV-vis spectroscopy and other analytical methods
• Interpersonal skills and ability to contribute to the success of a team
• Strong written and verbal communication skills
• Time management skills and ability to meet deadlines
• Additional analytical techniques: cIEF, mass spec, ELISA, bioassay, peptide mapping
• Experience with solid dosage form analysis (i.e. dissolution, particle sizing)
• Experience in GLP or GMP environment
• Management of external CROs/CMOs a plus

We invite qualified candidates to submit their CV to: recruiting@appliedmt.com (note: ‘Please put job title in subject heading)

AMT is an equal opportunity employer. In accordance with applicable law, AMT does not discriminate in hiring or otherwise in employment based on race, color, religion, sex, national origin, age, marital or veteran status, disability, sexual orientation, or any other legally protected status. EOE/AA/Vets

Position Summary:

Applied Molecular Transport is seeking a Head of Preclinical Biology to lead the advancement of AMT’s pipeline from research to the clinic.

Key Responsibilities:

• Responsible for establishing research and early clinical development capabilities across all therapeutic areas.
• Strategic and functional leader across biology, pharmacology, toxicology, bioanalytical and biomarker development.
• Lead non-clinical, IND/CTA-enabling and clinical studies across above-mentioned functions.
• In partnership with the clinical team, defined clinical plans, synopsis and protocols; responsible for non-clinical sections for investigator’s brochure and investigational medicinal product dossier.
• Work closely with CEO, CSO and CMO to influence, steer and track progress across all functional and therapeutic areas.
• Make marketing presentations of AMT’s programs to prospective partners and investors.

Preferred Education/Experience:

• PhD in relevant scientific discipline
• At least 10 years of industry experience
• Demonstrated ability to drive therapeutic development from early research to clinic

Knowledge, Skills and Abilities:

• Broad knowledge and experience in all stages of target discovery and drug development.
• Extensive experience in establishing and driving research strategies across multiple therapeutic areas, including diabetes, metabolic, liver, autoimmune and inflammatory diseases.
• Demonstrated success in initiating, building and advancing novel research and target platforms to mature target discovery and clinical programs.
• Strong leadership in building, motivating, and managing high-performing research organizations and multi-disciplinary teams.
• Skilled at attracting, retaining, leading, inspiring and mentoring scientists.
• Scientific and strategic driver of external collaborations with academic and industry, and proven track record in building strong relationship with key opinion leaders.
• Extensive experience in identifying relevant consultants and identification & engagement of relevant CROs for coordination & development of research activities.

We invite qualified candidates to submit their CV to: recruiting@appliedmt.com (note: ‘Please put job title in subject heading)

AMT is an equal opportunity employer. In accordance with applicable law, AMT does not discriminate in hiring or otherwise in employment based on race, color, religion, sex, national origin, age, marital or veteran status, disability, sexual orientation, or any other legally protected status. EOE/AA/Vets