Research Associate/Scientist

Position Summary:

Applied Molecular Transport, Inc. is looking to hire a research associate in analytical method development and quality control (AD & QC) for its therapeutic programs. The successful candidate will have extensive understanding of protein chemistry, protein characterization, and analytical techniques. The position will involve regular communication and collaboration with an interdisciplinary team within AMT and with outside contractors/consultants.

Key Responsibilities:

  • Perform analytical method development for LC based assays such as SEC, IEX and reversed-phase HPLC, and other protein-based analysis (i.e. SDS-PAGE, western blot, A280)
  • Provide testing support for the in-house manufacture of drug substance and drug product
  • Execute stability studies to evaluate and characterize protein degradation during storage
  • Process data and present findings at regular team meetings
  • Write technical reports
  • Document operating procedures for technology transfer and work with CROs/CMOs to implement methods in a GMP environment

Preferred Education/Experience:

  • BS, MS, PhD or equivalent degree in chemistry, biochemistry, biological sciences, pharmaceutical sciences or a related discipline
  • 1-5 years of experience in the biotech/pharmaceutical industry

Knowledge, Skills and Abilities:

  • Practical experience with protein chemistry, degradation and stabilization mechanisms
  • Experience with HPLC, electrophoresis, UV-vis spectroscopy and other analytical methods
  • Interpersonal skills and ability to contribute to the success of a team
  • Strong written and verbal communication skills
  • Time management skills and ability to meet deadlines
  • Additional analytical techniques: cIEF, mass spec, ELISA, bioassay, peptide mapping
  • Experience with solid dosage form analysis (i.e. dissolution, particle sizing)
  • Experience in GLP or GMP environment
  • Management of external CROs/CMOs a plus

We invite qualified candidates to submit their CV to: recruiting@appliedmt.com (note: ‘Please put job title in subject heading)