Senior Research Associate, Protein Production/Purification

Position Summary:

 We are seeking a skilled and experienced researcher to join a team focused on the expression and characterization of novel biologic drug candidates that modulate inflammation for the treatment of human diseases.

The successful candidate will be responsible for expressing, purifying, and characterizing recombinant proteins in support of discovery and preclinical development programs. Demonstrable experience with protein purification techniques and protein analytical/characterization methods is required. Experience with growth and transfection of mammalian cells up to liter scale for protein production will be a significant asset. Strong data analysis skills, the ability to prepare written reports, the ability to present results at research team meetings, and the ability to work productively and collaboratively within a tight-knit team are key assets for this position.

Key Responsibilities:

  • Strong scientific grounding in protein chemistry and protein structure and function.
  • Production of recombinant proteins up to liter scale from mammalian cell lines (e.g., CHO cells and HEK cells).
  • Experience with bacterial expression and refolding of proteins highly desirable.
  • Laboratory experience in protein purification (e.g. affinity chromatography, size exclusion chromatography, ion exchange chromatography).
  • Laboratory experience in protein analytical techniques (e.g., SDS-PAGE, HPLC, Western Blot).
  • Perform data analysis and summarize experimental results, with supervision as appropriate.
  • Prepare and maintain cell culture reagents and media
  • Ensure sufficient laboratory supplies for daily laboratory operations
  • Organize, record and maintain experimental data
  • Ensure proper operation and perform routine maintenance of laboratory equipment.
  • Assist other staff to complete laboratory tasks as necessary.
  • Maintain a clean and safe work environment

Preferred Education/Experience:

  • S. in Biochemical, Chemical, and Biology related discipline with 4-6 years of relevant experience or an MS with 2-4 years, or PhD with 0-2 years.
  • Title and salary will be commensurate with the candidate’s qualifications.

Knowledge, Skills and Abilities:

  • Must have excellent organization skills and ability to handle multiple tasks.
  • Highly motivated, willingness to acquire new skills and ability to work with minimal supervision.
  • Excellent verbal and written communication skills
  • Must be proficient in Microsoft Word, Excel, etc.

We invite qualified candidates to submit their CV to: recruiting@appliedmt.com (note: ‘Please put job title in subject heading)